Summary of Dr. Angus Robinson talking about RADICALS

00:00:00 - 00:30:00

Dr. Angus Robinson discusses the benefits and drawbacks of radiation therapy for prostate cancer patients. He recommends that patients consult with a urologist to discuss the best course of action for their individual situation.

• 00:00:00 The trial was looking at how effective radiotherapy is at preventing prostate cancer from coming back after a radical prostatectomy. The trial was divided into two groups: those who received radiotherapy straight away after their operation, and those who were randomized to receive salvage radiotherapy if their psa rose after their operation. The main outcome measure was whether or not there was a recurrence, defined as a psa value of greater than 2 after any radiotherapy. There were no overall differences in the outcomes between the two groups, but the radiotherapy group had a lower incidence of biochemical recurrences (defined as a psa value of greater than 2 after any radiotherapy).
• 00:05:00 Dr. Angus Robinson discusses the results of a large randomized trial that found that there is no difference between the outcomes of patients who received radiotherapy immediately after surgery or those who delayed radiotherapy for a period of time. He notes that the study showed a decrease in the number of patients who had a biochemical relapse, but cautions that this does not mean that radiotherapy is not beneficial for high-risk patients.
• 00:10:00 Dr. Angus Robinson discusses the benefits and risks of radiation therapy for prostate cancer patients. He recommends that prostate cancer patients who have had radiation therapy for other cancers consult with a urologist to discuss the best radiation therapy for their individual situation.
• 00:15:00 Dr. Angus Robinson discusses the benefits and drawbacks of various treatment options for patients with oligometastatic prostate cancer. He advises patients to ask their doctors about the best course of action for them and to consider using Cyberknife if they have a small, discrete lesion. He also notes that there is currently no evidence to support the use of immunotherapy in prostate cancer.
• 00:20:00 Dr. Angus Robinson discusses the role of hormone therapy in the salvage setting after surgery. He notes that hormone therapy can be beneficial for patients with a high psa, but warns that it may also lead to a prostate enlargement.
• 00:25:00 Radical prostate surgery can have side effects, and hormonal therapy may be necessary in some cases. The likelihood of this becoming more widely available through the NHS is unknown, but other options are available.
• 00:30:00 In this YouTube video, Dr. Angus Robinson discusses RADICALS, a new type of vaccine which is better tolerated and has fewer side effects than traditional vaccines. He says that, if we are completely honest, all traditional vaccines are equivalent in their effect. He also says that next year, Zoom meetings will be held to spread the geography even further.