Summary of Metabolism | Glycolysis

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This video discusses the role of enzymes in the metabolism of glycolysis, a process by which glucose is broken down to produce ATP. The different enzymes involved in this process are discussed, as well as the byproducts of the reaction.

  • 00:00:00 In this video, metabolism ninja nerds discuss glycolysis, a process by which glucose is oxidized to produce energy in the form of ATP. Glucose is brought into cells by blood transports, and three types of receptors are identified: glut1, glut2, and glut3. These receptors bind to different molecules in different tissues, and each receptor has a specific role in the metabolism of glucose. Finally, the p4 placenta, neuron, and kidney are all identified, along with their respective receptors.
  • 00:05:00 This video explains the role of glut transporters in glycolysis. Glut transporters are bi-directional and responsible for transferring glucose into and out of cells. Glucokinase and hexokinase are two enzymes that are involved in this process.
  • 00:10:00 The three-carbon molecule dihydroxyacetone phosphate is synthesized from glucose 6-phosphate and fructose 6-phosphate by a phospho fructose kinase enzyme. This molecule is important in glycolysis because it is the precursor to two other important molecules: fructose 1,6-bisphosphate and glucose 6-phosphate. The molecule is called dihydroxyacetone phosphate because it has two hydroxyl groups attached to each carbon.
  • 00:15:00 The glycolytic pathway involves the conversion of glucose into glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. This process is catalyzed by a triose phosphate isomerase enzyme.
  • 00:20:00 The video discusses the metabolism of glycolysis, which involves the breakdown of glucose to produce two molecules of NADH and two molecules of ATP. The different enzymes involved in this process are discussed, including phosphoglycerate mutase, phospho glycerate kinase, and phosphoenolpyruvate mutase.
  • 00:25:00 In this video, the metabolic process of glycolysis is explained. The enzyme responsible for this reaction is pyruvate kinase, and it is a highly regulated enzyme. The glycolysis step is not reversible, and one of the byproducts of this reaction is lactic acid. Lactic acid can be converted into glucose or ATP, depending on the body's demands.
  • 00:30:00 The author discusses how glycolysis occurs in the cell, describing its starting substrate, end product, and byproducts. He also discusses anaerobic conditions and how glycolysis can lead to lactic acidosis.

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