Retinoids are well-studied compounds that promote collagen and elastic fiber formation, reduce wrinkles and sagging, fade dark patches, reduce acne, and have anti-skin cancer effects. However, they can also cause dryness and irritation, making it essential to begin slowly by mixing a green-pea sized amount with moisturizer every other night. Retinoids should not be used during pregnancy as they could cause fetal harm. Apply it at bedtime, avoid using other acidic products at the same time, and use moisturizers throughout the day to combat the drying effects of retinoids. A reputable over-the-counter retinoid product recommended by the dermatologist is Differin Gel, which is effective and reasonably priced.