Summary of Andrew Nelson: Using large-scale comparative -omic analyses to uncover functional elements ...

00:00:00 - 00:40:00

Professor Andrew Nelson discusses how large-scale comparative -omic analyses can be used to uncover functional elements in biological systems. He gives the example of how this technique was used to identify a conserved link RNA that is involved in plant growth and sea germination.

• 00:00:00 This lecture by Andrew Nelson covers the long-term coding rnas, also known as rRNA or RNA transcripts, which are important for regulating responses to environmental changes. Nelson also discusses other rRNA transcripts that play roles in chromatin dynamics and gene expression.
• 00:05:00 Andrew Nelson has identified functional elements in plants using large-scale comparative -omic analyses. These analyses have identified a long list of well-characterized link rnas in plants, many of which are present in human genomes. This information is important for understanding the functions of these rnas and for developing methods for their identification and characterization.
• 00:10:00 The video discusses how large-scale comparative -omic analyses can be used to identify functional elements in biological systems. One example is the identification of a conserved link RNA that is involved in plant growth and sea germination.
• 00:15:00 The study investigated the relationship between small RNA molecules and gene expression in response to stress. They found that a subset of the small RNA molecules correlated with gene expression, and that some of these correlations changed in response to stress.
• 00:20:00 The presenter discusses large-scale comparative genomic analyses, which can be used to uncover functional elements in genes. They discuss a study in which they used a germination screen to identify genes that are associated with a decrease in germination rates.
• 00:25:00 The video discusses the use of large-scale comparative -omic analyses to uncover functional elements. It discusses how two independent TDA insertions into the gene lgd1 disrupt its expression and affect the germination of seeds, as well as the production of novel peptides.
• 00:30:00 Andrew Nelson and his team used large-scale comparative -omic analyses to uncover functional elements in peptides involved in the germination process. They found that a peptide that is highly conserved across all brassicasey and that is concerned across all grass caves is important for the germination process. They also found that a transcript for this peptide is present in seeds and that limited proteolysis of the peptide produces different size peptides. If this peptide is actually interacting with proteins in the extract, it could lead to a better understanding of its function.
• 00:35:00 Andrew Nelson discusses how large-scale comparative -omic analyses can be used to uncover functional elements in a transcriptome. This information can be used to better understand how different environmental stresses affect the organism.
• 00:40:00 In this video, Professor Andrew Nelson discusses his work using large-scale comparative -omic analyses to uncover functional elements. He notes that, while there is much still to be discovered, what is known about stress-responsive elements and ciliates so far is deeply conserved.