Summary of Fisiología -Transporte de O2 y CO2 en sangre y líquidos tisulares | Parte 2

00:00:00 - 00:05:00

This section of the video discusses the relationships between oxygen and carbon dioxide in the blood and tissue fluids during intense exercise. The percentage of oxygen carried by the blood when it passes through capillaries, known as the coefficient of utilization, is typically 25%, but can increase to up to 75-85% during extreme exercise situations. The oxygen is carried by hemoglobin, which also functions as a tissue oxygen amortigator. The disassociation curve of oxygen-hemoglobin refers to the normal media and can be influenced by various factors such as pH, carbon dioxide concentration, temperature, and inorganic phosphate levels. These factors can shift the disassociation curve, impacting the liberation of oxygen from the blood to tissues and overall oxidation. The opposite happens in the lungs, where carbon dioxide diffuses from the blood into the alveoli, reducing the blood carbon dioxide pressure and allowing hemoglobin to bind more oxygen, facilitating oxygen transport to the tissues, while the Bohr effect describes how oxygen binding to hemoglobin displaces carbon dioxide from the blood and aids in carbon dioxide transport. The layout and the title of the content matches the mentioned YouTube video "Fisiología -Transporte de O2 y CO2 en sangre y líquidos tisulares | Parte 2".

• 00:00:00 In this section of the video, the speaker discusses the percentage of oxygen carried by the blood when it passes through capillaries. Known as the "coefficient of utilization," this value is typically 25%, meaning that 25% of the oxygen carried by the blood is used by tissues during intense exercise. However, this value can increase to up to 75-85% during extreme exercise situations. The speaker also states that while hemoglobin is necessary for the transportation of oxygen to tissues, it also functions as a tissue oxygen amortigator, meaning it plays a crucial role in maintaining a constant pressure of oxygen in the tissues. The speaker then discusses the disassociation curve of oxygen-hemoglobin, which refers to the normal media and can be influenced by various factors such as pH, carbon dioxide concentration, temperature, and inorganic phosphate levels. These factors can shift the disassociation curve, impacting the liberation of oxygen from the blood to tissues and overall oxidation.
• 00:05:00 In this section, the video discusses the transportation of oxygen and carbon dioxide in the blood and tissue fluids. When blood passes through the tissues, carbon dioxide diffuses from the tissue cells into the blood, increasing the blood carbon dioxide pressure and the concentration of carbonic acid and hydrogen ions. This shifts the oxygen dissociation curve downward and to the right, causing oxygen to dissociate from hemoglobin and release more oxygen to the tissues. The opposite occurs in the lungs, where carbon dioxide diffuses from the blood into the alveoli, reducing the blood carbon dioxide pressure and the concentration of hydrogen ions. This shifts the oxygen dissociation curve upward and to the left, allowing hemoglobin to bind more oxygen and facilitating oxygen transport to the tissues. The video also mentions the Bohr effect, which describes how oxygen binding to hemoglobin displaces carbon dioxide from the blood and aids in carbon dioxide transport. Additionally, it explains how the combination of hemoglobin with carbon monoxide reduces the capacity of oxygen transport in the blood, as carbon monoxide has a higher affinity for hemoglobin than oxygen. This information is important to understand the effects of carbon monoxide poisoning and the need for oxygen therapy.