Summary of Salmonella typhi Part 2; Pathophysiology, Type-III secretion system, symptoms, diagnosis, treatment

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Salmonella typhi is a bacteria that causes typhoid fever, which is a fever accompanied by diarrhea. The standard diagnostic test is a blood or stool culture. Salmonella typhi can also be detected using the cytos Lysine Deoxytronate media. Symptoms of typhoid fever include fever, weakness, stomach pain, headache, diarrhea, and constipation. The salmonella typhi Vidal Test is a method for determining whether a patient has the salmonella typhi infection, and is positive if the o antigen is tighter than 1 to 160 or if the h antigen titans greater than 1 to 160. The vital test is positive if the egg detonation phenomena is present. The antibiotics of choice are ciprofloxacin and cotrimexial, which have fewer side effects than the clone of finacle.

  • 00:00:00 The type 3 secretion system is a specialized system found in Salmonella typhi that helps the bacteria enter and replicate inside host cells.
  • 00:05:00 Salmonella typhi has an inner ring structure and an outer ring structure, and the proteins within these structures work together to form the rod-like structure seen on the surface of the bacteria. The type 3 secretion system is responsible for the virulence factors that are present in the Salmonella, and it is through this system that the cytokine expression in macrophages is suppressed. Salmonella typhi also hasWireless factors, also known as effectors, which play a role in the establishment of the bacteria in the human host, among other things.
  • 00:10:00 The type III secretion system is an important protein within Salmonella, and one of its proteins, the avr, is responsible for inhibiting the key pro-inflammatory transcription factor, nfk. This suppresses epithorosis in infected macrophages, allows for establishment of the bacteria within the host cell, and influences the function of the intestinal cells' tight junctions. The typhoid toxin, thyphytoxin, is responsible for the death of intestinal cells, leading to diarrhea.
  • 00:15:00 Salmonella typhi is a bacteria that causes typhoid fever, which is a fever accompanied by diarrhea. The standard diagnostic test is a blood or stool culture. Salmonella typhi can also be detected using the cytos Lysine Deoxytronate media. Symptoms of typhoid fever include fever, weakness, stomach pain, headache, diarrhea, and constipation.
  • 00:20:00 The salmonella typhi Vidal Test is a method for determining whether a patient has the salmonella typhi infection, and is positive if the o antigen is tighter than 1 to 160 or if the h antigen titans greater than 1 to 160. The vital test is positive if the egg detonation phenomena is present. The antibiotics of choice are ciprofloxacin and cotrimexial, which have fewer side effects than the clone of finacle.

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