Summary of manipulación genética en ratones

00:00:00 - 00:05:00

The use of genetic manipulation in rats has been key to research before modern genetic technology. Rats are raised in a similar way to humans, so they are an ideal species to study changes caused by genetic modification. Manipulating genes can lead rats to develop diseases that they wouldn't naturally get, which has been helpful in understanding previous research. Two rat types that have made significant contributions to human health have been knock rat and nocaut. Knock rats were created by adding a foreign gene, and nocaut rats had one or more genes disabled. These two rat types have been able to replicate 500 diseases in humans, and as a result, have been able to help combat some of the most important diseases that have been studied in rats. This technology continues to advance, and there are now efforts being made to develop treatments that can correct the effects of disease in humans. Genetic manipulation of rats has been a major contributor to human knowledge, and as a result, has helped us make significant advances in the identification and prevention of diseases.

• 00:00:00 This video presents the importance of genetic manipulation in rats and discusses the history of this technology. Three pioneers of genetic manipulation are discussed- Martin Edward Evans, Mario Campeche, and Oliver Smithies. All three pioneers used methods to isolate and manipulate cells in order to study gene function. Today, genetic manipulation is used for a variety of purposes, including creating healthier organisms, reversing diseases, and optimizing human DNA. Rats are a particularly useful model for research because of their similarities to humans. Genetic manipulation has helped researchers understand the physiology and pathology of human diseases in a more precise way than ever before.
• 00:05:00 The video discusses the use of genetic manipulation in rats, which has been key to research before modern genetic technology. Rats are raised in a similar way to humans, so they are an ideal species to study changes caused by genetic modification. Manipulating genes can lead rats to develop diseases that they wouldn't naturally get, which has been helpful in understanding previous research. Two rat types that have made significant contributions to human health have been knock rat and nocaut. Knock rats were created by adding a foreign gene, and nocaut rats had one or more genes disabled. These two rat types have been able to replicate 500 diseases in humans, and as a result, have been able to help combat some of the most important diseases that have been studied in rats. This technology continues to advance, and there are now efforts being made to develop treatments that can correct the effects of disease in humans. Genetic manipulation of rats has been a major contributor to human knowledge, and as a result, has helped us make significant advances in the identification and prevention of diseases.